Integration of HPV Vaccination and HPV-based Cervical Screening Into ARV Clinics: the H2VICTORY Trial

PHASE3Not yet recruitingINTERVENTIONAL
Enrollment

8,000

Participants

Timeline

Start Date

February 1, 2023

Primary Completion Date

June 30, 2027

Study Completion Date

June 30, 2027

Conditions
HPV Infection
Interventions
BIOLOGICAL

HPV vaccine

Licensed HPV vaccines (bivalent, quadrivalent, or nonvalent) available in the country of the study site

DIAGNOSTIC_TEST

HPV testing

HPV testing with partial genotyping of HPV16/18 (and/or 45) to be used as a primary cervical screening test for all participants regardless of the study arm

BIOLOGICAL

HAV vaccine

Hepatitis A virus (HAV) vaccine to be offered as a placebo

All Listed Sponsors
collaborator

University of New Mexico

OTHER

collaborator

University of Stellenbosch

OTHER

collaborator

University of KwaZulu

OTHER

collaborator

Coptic Hope Center

UNKNOWN

collaborator

Emory University

OTHER

collaborator

Ministry of Health, Swaziland

OTHER_GOV

collaborator

Baylor College of Medicine Children's Foundation

UNKNOWN

collaborator

Sefako Makgatho Health Sciences University

OTHER

collaborator

Aga Khan University

OTHER

collaborator

World Health Organization

OTHER

lead

International Agency for Research on Cancer

OTHER

NCT05173324 - Integration of HPV Vaccination and HPV-based Cervical Screening Into ARV Clinics: the H2VICTORY Trial | Biotech Hunter | Biotech Hunter