PA3-17 Injection Treatment of Adult Patients With CD7-positive Relapsed/Refractory Lymphoid Hematologic Malignancies

PHASE1UnknownINTERVENTIONAL
Enrollment

22

Participants

Timeline

Start Date

December 1, 2021

Primary Completion Date

December 1, 2022

Study Completion Date

December 1, 2024

Conditions
CD7-positive Relapsed/Refractory Lymphoid Hematologic Malignancies
Interventions
BIOLOGICAL

T cell injection targeting CD7 chimeric antigen receptor

The subjects, who sign the informed consent forms and been screened by inclusion/exclusion criteria, will be assigned into 0.5 × 106, 2.0 × 106 and 4.0 × 106 CAR-T/kg groups in order of sequence. And the subjects will be administered once.

Trial Locations (1)

230088

RECRUITING

PersonGen.Anke Cellular Therapeutice Co., Ltd., Hefei

All Listed Sponsors
collaborator

The First Affiliated Hospital of Zhengzhou University

OTHER

collaborator

Peking University People's Hospital

OTHER

collaborator

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

OTHER

collaborator

Hematology Hospital of Chinese Academy of Medical Sciences (Hematology Research Center of Chinese Academy of Medical Sciences)

UNKNOWN

collaborator

Zhejiang University

OTHER

lead

PersonGen BioTherapeutics (Suzhou) Co., Ltd.

INDUSTRY