Preserving Kidney Function in Children With Chronic Kidney Disease

CompletedOBSERVATIONAL
Enrollment

20,240

Participants

Timeline

Start Date

September 22, 2023

Primary Completion Date

July 31, 2024

Study Completion Date

July 31, 2024

Conditions
Chronic Kidney Disease Stage 2Chronic Kidney Disease Stage 3Pediatric Kidney Disease
Interventions
DIAGNOSTIC_TEST

Blood pressure

The first anti-hypertensive prescribed will be categorized as ACEi, ARB, thiazide diuretic, loop diuretic, beta-blocker, calcium channel blocker, other, and none; secondary analyses will combine ACEi and ARB into a single RAAS blocker category. We will conduct additional secondary analyses for specific medications with sufficient sample sizes.

DIAGNOSTIC_TEST

Urine protein

Evaluating urine protein for children with CKD and hypertension is another guideline recommendation, but the frequency, type of assessment (qualitative or quantitative urine protein), and utility for patients without hypertension are unclear. We will determine whether urine protein is evaluated at each encounter and create a dichotomous indicator.

Trial Locations (1)

19103

Children's Hospital of Philadelphia, Philadelphia

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Patient-Centered Outcomes Research Institute

OTHER

collaborator

Children's Hospital Medical Center, Cincinnati

OTHER

collaborator

Ann & Robert H Lurie Children's Hospital of Chicago

OTHER

collaborator

Nationwide Children's Hospital

OTHER

collaborator

Seattle Children's Hospital

OTHER

collaborator

Stanford University

OTHER

collaborator

University of Colorado, Denver

OTHER

collaborator

Duke University

OTHER

collaborator

University of North Carolina, Chapel Hill

OTHER

collaborator

Indiana University

OTHER

collaborator

Medical College of Wisconsin

OTHER

collaborator

University of Iowa

OTHER

collaborator

Johns Hopkins University

OTHER

collaborator

University of Michigan

OTHER

collaborator

University of Florida

OTHER

collaborator

University of Miami

OTHER

collaborator

University of Pennsylvania

OTHER

collaborator

Alfred I. duPont Hospital for Children

OTHER

lead

Children's Hospital of Philadelphia

OTHER

NCT05169411 - Preserving Kidney Function in Children With Chronic Kidney Disease | Biotech Hunter | Biotech Hunter