NCT05169229View on ClinicalTrials.gov

Antibiotic Impregnated Bone Graft to Reduce Infection in Hip Replacement.

PHASE2/PHASE3RecruitingINTERVENTIONAL
Enrollment

1,100

Participants

Timeline

Start Date

April 1, 2022

Primary Completion Date

December 31, 2028

Study Completion Date

December 31, 2031

Conditions
Arthroplasty, Replacement, HipOsteoarthritis, HipAntibiotic Resistant InfectionProsthetic Joint Infection
Interventions
DRUG

Vancomycin + Tobramycin

1 g vancomycin (powder) diluted in 8 ml tobramycin (40 -80mg/ml). Added to the prepared allograft before the allograft is used during the revision surgery.

DRUG

Saline

As a placebo added to the allograft.

Trial Locations (1)

58185

RECRUITING

Universitetssjukhuset Linköping, Linköping

All Listed Sponsors
collaborator

Region Östergötland

OTHER

collaborator

The Swedish Research Council

OTHER_GOV

lead

University Hospital, Linkoeping

OTHER