Timely Intravenous Magnesium for Asthma in Children

PHASE2CompletedINTERVENTIONAL
Enrollment

52

Participants

Timeline

Start Date

September 12, 2022

Primary Completion Date

May 31, 2023

Study Completion Date

July 31, 2023

Conditions
Asthma
Interventions
DRUG

Magnesium Sulfate, Heptahydrate

A single dose of intravenous magnesium sulfate given over 20 minutes through a peripheral intravenous line. Two arms of the study will deliver intravenous magnesium, one at a dose of 50 mg/kg, and the other at a dose of 75 mg/kg.

DRUG

0.9% saline

A single dose of intravenous 0.9% sodium chloride given over 20 minutes through a peripheral intravenous line as the placebo arm of the study.

Trial Locations (3)

19104

Children's Hospital of Philadelphia, Philadelphia

43205

Nationwide Children's Hospital, Columbus

84010

Primary Children's Hospital, Salt Lake City

All Listed Sponsors
collaborator

Children's Hospital of Philadelphia

OTHER

collaborator

Nationwide Children's Hospital

OTHER

collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH

lead

University of Utah

OTHER