BESTMED: Observational Evaluation of Second Line Therapy Medications in Diabetes

UnknownOBSERVATIONAL
Enrollment

550,000

Participants

Timeline

Start Date

July 1, 2021

Primary Completion Date

June 30, 2024

Study Completion Date

June 30, 2024

Conditions
Diabetes Mellitus, Type 2
Interventions
DRUG

DPP4

Dipeptidyl peptidase-4 inhibitors (DPP4) including alogliptin, linagliptin, sitagliptin, and saxagliptin

DRUG

GLP-1 receptor agonist

Glucagon-like peptide-1 receptor agonists (GLP1-RA) including dulaglutide, exenatide, liraglutide and semaglutide

DRUG

Basal Insulin

degludec, detemir, glargine and NPH

DRUG

SLGT2

Sodium-glucose cotransporter-2 inhibitors (SLGT2) including canagliflozin, dapagliflozin, empagliflozin, and ertugliflozin

DRUG

SU

Sulfonylurea (SU) including glimepiride, glipizide, and glyburide

Trial Locations (5)

19801

RECRUITING

HealthCore, Inc., Wilmington

44122

RECRUITING

Greater Plains Collaborative, Beachwood

75246

RECRUITING

Baylor Scott & White, Dallas

40512-4611

RECRUITING

Humana, Lexington

02115

RECRUITING

Brigham and Women's Hospital, Boston

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Patient-Centered Outcomes Research Institute

OTHER

collaborator

Baylor College of Medicine

OTHER

collaborator

Baylor Scott and White Research Institute

UNKNOWN

collaborator

The Cleveland Clinic

OTHER

collaborator

HealthCore, Inc.

INDUSTRY

collaborator

Humana Inc.

INDUSTRY

collaborator

Massachusetts General Hospital

OTHER

collaborator

Medical Outcomes Management

UNKNOWN

collaborator

University of Iowa

OTHER

collaborator

Allina Health

UNKNOWN

collaborator

Intermountain Health Care, Inc.

OTHER

collaborator

Marshfield Clinic

UNKNOWN

collaborator

Medical College of Wisconsin

OTHER

collaborator

University of Missouri-Columbia

OTHER

collaborator

University of Utah

OTHER

lead

Brigham and Women's Hospital

OTHER

NCT05161429 - BESTMED: Observational Evaluation of Second Line Therapy Medications in Diabetes | Biotech Hunter | Biotech Hunter