Comparing Platelet Rich Plasma and Corticosteroid for Military & Civilian Patients With Glenohumeral Osteoarthritis

PHASE3CompletedINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

September 26, 2022

Primary Completion Date

May 8, 2025

Study Completion Date

May 8, 2025

Conditions
Osteoarthritis of the ShoulderCorticosteroidPRPPain
Interventions
BIOLOGICAL

Platelet Rich Plasma Injection

"Minimum 2cc Leukocyte Poor Platelet Rich Plasma~The PRP will be prepared by drawing 60cc blood from the participant through venipuncture, spinning the blood sample in a centrifuge and then injecting the platelet rich plasma (approximately 2-5cc or max collected) into the study shoulder using ultrasound guidance. This sample will be prepared by the study provider (physician assistant or physician). Any leftover blood will be safely discarded per standard protocols."

BIOLOGICAL

Corticosteroid Injection

5cc Normal Saline + 2cc 10 mg/ml Triamcinolone Acetonide (Kenalog)

BIOLOGICAL

Delayed Platelet Rich Plasma Injection After Corticosteroid Injection Failure

Participants randomized to the corticosteroid injection (CSI) group who report no improvement in their pain level at the 6 week post-CSI visit will be unblinded to their study injection (CSI) and will be offered the option to stay in the study and receive Platelet Rich Plasma injection.

Trial Locations (1)

20889

Walter Reed National Military Medical Center, Bethesda

All Listed Sponsors
collaborator

United States Naval Medical Center, San Diego

FED

collaborator

Brooke Army Medical Center

FED

collaborator

Uniformed Services University of the Health Sciences

FED

lead

Walter Reed National Military Medical Center

FED