50
Participants
Start Date
September 26, 2022
Primary Completion Date
May 8, 2025
Study Completion Date
May 8, 2025
Platelet Rich Plasma Injection
"Minimum 2cc Leukocyte Poor Platelet Rich Plasma~The PRP will be prepared by drawing 60cc blood from the participant through venipuncture, spinning the blood sample in a centrifuge and then injecting the platelet rich plasma (approximately 2-5cc or max collected) into the study shoulder using ultrasound guidance. This sample will be prepared by the study provider (physician assistant or physician). Any leftover blood will be safely discarded per standard protocols."
Corticosteroid Injection
5cc Normal Saline + 2cc 10 mg/ml Triamcinolone Acetonide (Kenalog)
Delayed Platelet Rich Plasma Injection After Corticosteroid Injection Failure
Participants randomized to the corticosteroid injection (CSI) group who report no improvement in their pain level at the 6 week post-CSI visit will be unblinded to their study injection (CSI) and will be offered the option to stay in the study and receive Platelet Rich Plasma injection.
Walter Reed National Military Medical Center, Bethesda
United States Naval Medical Center, San Diego
FED
Brooke Army Medical Center
FED
Uniformed Services University of the Health Sciences
FED
Walter Reed National Military Medical Center
FED