372
Participants
Start Date
December 20, 2021
Primary Completion Date
October 30, 2024
Study Completion Date
January 31, 2028
pegylated liposomal doxorubicin (PLD)
pegylated liposomal doxorubicin (PLD) 30 mg/m\^2, i.v., d1, q3w
cyclophosphamide (C)
cyclophosphamide (C) 600 mg/m\^2, i.v., d1, q3w
trastuzumab (H)
trastuzumab (H) 8 mg/kg loading dose, 6 mg/kg maintenance doses, i.v., d1, q3w
pertuzumab (P)
pertuzumab (P) 840 mg loading dose, 420 mg maintenance doses, i.v., d1, q3w
docetaxel (T)
docetaxel (T) 90\~100 mg/m\^2, i.v., d1, q3w
docetaxel (T)
docetaxel (T) 75 mg/m\^2, i.v., d1, q3w
carboplatin (Cb)
carboplatin (Cb) AUC 6, i.v., d1, q3w
trastuzumab (H)
trastuzumab (H) 8 mg/kg loading dose, 6 mg/kg maintenance doses, i.v., d1, q3w
pertuzumab (P)
pertuzumab (P) 840 mg loading dose, 420 mg maintenance doses, i.v., d1, q3w
RECRUITING
Sunyat-sen Memorial Hospital, Guandong
Collaborators (1)
CSPC Ouyi Pharmaceutical Co., Ltd.
INDUSTRY
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
OTHER