Cerebral Hemodynamics and Microemboli During Placement of Relay®Branch Thoracic Stent-Graft System

Active, not recruitingOBSERVATIONAL
Enrollment

20

Participants

Timeline

Start Date

December 15, 2021

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
Thoracic Aortic AneurysmThoracic Aortic DissectionMicroemboli
Interventions
OTHER

transcranial Doppler ultrasonography (TCD)

"Transcranial Doppler (TCD) is a non-invasive ultrasound-based technique that facilitates insonation of the cerebral arteries. TCD probe design enables continuous monitoring of cerebral blood flow velocity (CBFv). TCD has a variety of clinical applications, including intraoperative monitoring for detection of microemboli. The TCD probe can be comfortably secured to the patient's head by a headframe in order to maintain continuous vessel insonation. Microembolic signals (MES) can be reliably detected based on standard criteria:~1. Brief in duration (\<300msec)~2. High intensity (amplitude \>3 dB above background)~3. Unidirectional~4. Audible chirp or snap~Further, CBFv monitoring during may inform flow perturbations that occur during cardiac or vascular manipulations."

Trial Locations (2)

19104

Hospital of the University of Pennsylvania, Philadelphia

Penn Presbyterian Medical Center, Philadelphia

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Bolton Medical

INDUSTRY

lead

University of Pennsylvania

OTHER

NCT05155956 - Cerebral Hemodynamics and Microemboli During Placement of Relay®Branch Thoracic Stent-Graft System | Biotech Hunter | Biotech Hunter