20
Participants
Start Date
December 15, 2021
Primary Completion Date
December 31, 2026
Study Completion Date
December 31, 2026
transcranial Doppler ultrasonography (TCD)
"Transcranial Doppler (TCD) is a non-invasive ultrasound-based technique that facilitates insonation of the cerebral arteries. TCD probe design enables continuous monitoring of cerebral blood flow velocity (CBFv). TCD has a variety of clinical applications, including intraoperative monitoring for detection of microemboli. The TCD probe can be comfortably secured to the patient's head by a headframe in order to maintain continuous vessel insonation. Microembolic signals (MES) can be reliably detected based on standard criteria:~1. Brief in duration (\<300msec)~2. High intensity (amplitude \>3 dB above background)~3. Unidirectional~4. Audible chirp or snap~Further, CBFv monitoring during may inform flow perturbations that occur during cardiac or vascular manipulations."
Hospital of the University of Pennsylvania, Philadelphia
Penn Presbyterian Medical Center, Philadelphia
Collaborators (1)
Bolton Medical
INDUSTRY
University of Pennsylvania
OTHER