A Study to Evaluate the Efficacy and Safety of AK120 in the Treatment of Subjects With Moderate-to-severe Asthma

PHASE2TerminatedINTERVENTIONAL
Enrollment

1

Participants

Timeline

Start Date

February 11, 2022

Primary Completion Date

August 5, 2022

Study Completion Date

August 5, 2022

Conditions
Asthma
Interventions
BIOLOGICAL

AK120

AK120 regimen 1-subcutaneous injection every two weeks up to week 24, and follow up to week 32.

BIOLOGICAL

AK120

AK120 regimen 2(first dose doubling)-subcutaneous injection and then every two weeks up to week 24, and follow up to week 32.

BIOLOGICAL

AK120

AK120 regimen 3(first dose doubling)-subcutaneous injection and then every two weeks up to week 24, and follow up to week 32.

BIOLOGICAL

Placebo

Placebo subcutaneous injection every two weeks up to week 24, and follow up to week 32.

Trial Locations (19)

Unknown

The Second Hospital of Anhui Medical University, Hefei

Beijing Jingmei General Hospital, Beijing

The First Affiliated Hospital of Guangzhou Medical University, Guangzhou

The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou

Cangzhou People's Hospital, Cangzhou

The Second Hospital of Hebei Medical University, Shijiazhuang

Luoyang Central Hospital, Luoyang

Henan Provincial People's Hospital, Zhengzhou

Baogang Hospital, Inner Mongolia, China, Baotou

Inner Mongolia People's Hospital, Hohhot

Zhongda Hospital Southeast University, Nanjing

Jiangxi Provincial Prople's Hospita, Nanchang

Jiangxi Pingxiang People's Hospital, Pingxiang

Jilin Province People's Hospital, Changchun

Shanghai General Hospital, Shanghai

Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, Shanghai

Zhongshan Hospital Fudan University, Shanghai

First Hospital of Shanxi Medical University, Taiyuan

The Second Affiliated Hospital Zhejiang University School of Medicine,, Hangzhou

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Akeso

INDUSTRY

NCT05155020 - A Study to Evaluate the Efficacy and Safety of AK120 in the Treatment of Subjects With Moderate-to-severe Asthma | Biotech Hunter | Biotech Hunter