KN046 in Subjects With Advanced Pancreatic Ductal Adenocarcinoma.

PHASE3Active, not recruitingINTERVENTIONAL
Enrollment

408

Participants

Timeline

Start Date

January 20, 2022

Primary Completion Date

April 30, 2024

Study Completion Date

August 30, 2024

Conditions
Advanced Pancreatic Ductal Adenocarcinoma
Interventions
DRUG

KN046

KN046+Nab-Paclitaxel+Gemcitabine In combine therapy stage, KN046 is 5 milligram per kilogram, every 2 weeks. In maintain stage, KN046 is 5 milligram per kilogram, every 2 weeks.

DRUG

placebo

placebo+Nab-Paclitaxel+Gemcitabine In combine therapy stage, placebo is 5 milligram per kilogram, every 2 weeks. In maintain stage, placebo is 5 milligram per kilogram, every 2 weeks.

Trial Locations (65)

200433

Shanghai Changhai Hospital, Shanghai

Unknown

The Second Hospital Of Anhui medical University, Hefei

Beijing Cancer Hospital, Beijing

Beijing Friendship Hospital, Beijing

Cancer Hospital Chinese Academy of Medical Sciences, Beijing

Chinese PLA General Hospital, Beijing

Peking Union Medical College, Beijing

Peking University Third Hospital, Beijing

Chongqing Cancer Hospital, Chongqing

The First Affiliated Hospital of Chongqing Medical University, Chongqing

The Southwest Hospital of AMU, Chongqing

The Third Affiliated Hospital of Army Medical University, Chongqing

Fujian Cancer Hospital, Fuzhou

Fujian Medical University Union Hospital, Fuzhou

The First Affiliated Hospital of Fujian Medical University, Fuzhou

The First Affiliated Hospital of Xiamen University, Xiamen

The First Hospital of Lanzhou University, Lanzhou

Guangdong Provincial People's Hospital, Guangzhou

Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou

The First Affiliated Hospital,Sun Yat-sen University, Guangzhou

Affiliated Cancer Hospital of Guangxi Medical University, Nanning

The Affiliated Hospital of Guizhou Medical University, Guiyang

The Fourth Hospital of Hebei Medical University, Shijiazhuang

Harbin Medical University Cancer Hospital, Harbin

Henan Cancer Hospital, Zhengzhou

Henan Provincial People's Hospital, Zhengzhou

The First Affiliated Hospital of Zhengzhou University, Zhengzhou

Hubei Cancer Hospital, Wuhan

Renmin Hospital of Wuhan University, Wuhan

Union Hospital Tongji Medical College Huazhong University of Science And Technology, Wuhan

Zhongnan Hospital of Wuhan University, Wuhan

Hunan Cancer Hospital, Changsha

Hunan Provincial People's Hospital, Changsha

The Second Xiangya Hospital of Central South University, Changsha

Xiangya Hospital Central South University, Changsha

The First People's Hospital of Changzhou, Changzhou

Jiangsu Province Hospital, Nanjing

Nantong Tumor Hospital, Nantong

The Affiliated Hospital Of XuZhou Medical University, Xuzhou

First Affiliated Hospital of Nanchang University, Nanchang

The Second Affiliated Hospital of Nanchang University, Nanchang

China-Japan Union Hospital of Jilin University, Changchun

The First Hospital of Jilin University, Changchun

Liaoning Cancer Hospital, Shenyang

The First Affiliated Hospital of China Medical University, Shenyang

Shandong Cancer Hospital, Jinan

Shandong Provincial Hospital, Jinan

Affiliated Hospital of Jining Medical University, Jining

LINYI Cancer Hospital, Linyi

Linyi City People Hospital, Linyi

The Affiliated Hospital of Qingdao University, Qingdao

Weifang People'S Hospital, Weifang

Yueyang Hospital of Integrated Traditional Chinese and Western Medicine , Shanghai University of Traditional Chinese Medicine, Shanghai

Zhongshan Hospital Fudan University, Shanghai

Shanxi Cancer hospital, Taiyuan

Shanxi Provincial People's Hospital, Taiyuan

the First Affiliated Hospital of Xi'an Jiaotong University, Xi’an

Sichuan Cancer Hospital, Chengdu

Sichuan Provincial People's Hospital, Chengdu

Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou

The Second Affiliated Hosipital Zhejiang University School of Medicine, Hangzhou

Zhejiang Cancer Hospital, Hangzhou

Zhejiang Provincial People's hospital, Hangzhou

Jiaxing Second Hospital, Jiaxing

The First Affiliated Hospital of Wenzhou Medical University, Wenzhou

All Listed Sponsors
lead

Jiangsu Alphamab Biopharmaceuticals Co., Ltd

INDUSTRY