Albumin and Crystalloid Administration in Septic Shock

PHASE4RecruitingINTERVENTIONAL
Enrollment

2,426

Participants

Timeline

Start Date

January 17, 2022

Primary Completion Date

September 30, 2026

Study Completion Date

December 31, 2026

Conditions
Septic Shock
Interventions
DRUG

Treatment

For the treatment group, 200cc of 20% human albumin with 15 cc per kg of crystalloid will be administered over 1\~2h for initial fluid resuscitation. The treating physicians can choose the type of fluid, such as balanced fluid or isotonic saline.

DRUG

Placebo

For the control group, 30 cc per kg of crystalloid will be administered according to the usual practice. The treating physicians can choose the type of fluid, such as balanced fluid or isotonic saline.

Trial Locations (1)

05505

RECRUITING

Asan Medical Center, Seoul

Sponsors
All Listed Sponsors
collaborator

Samsung Medical Center

OTHER

collaborator

Gangnam Severance Hospital

OTHER

collaborator

Chungnam National University Hospital

OTHER

collaborator

Seoul National University Hospital

OTHER

collaborator

Seoul National University Bundang Hospital

OTHER

collaborator

SMG-SNU Boramae Medical Center

OTHER

collaborator

Hanyang University

OTHER

collaborator

Korea University Ansan Hospital

OTHER

lead

Asan Medical Center

OTHER