Study to Assess Adverse Events and Change in Disease State of Oral Venetoclax in Combination With Subcutaneous (SC) Azacitidine in Newly Diagnosed Adult Participants With Acute Myeloid Leukemia (AML) Who Are Ineligible for Intensive Chemotherapy in China

PHASE4Active, not recruitingINTERVENTIONAL
Enrollment

44

Participants

Timeline

Start Date

January 6, 2022

Primary Completion Date

March 31, 2026

Study Completion Date

March 31, 2026

Conditions
Acute Myeloid Leukemia (AML)
Interventions
DRUG

Venetoclax

Tablet: Oral

DRUG

Azacitidine

Subcutaneous Injection (SC)

Trial Locations (18)

100730

Peking Union Medical College Hospital (East) - Dongdan Campus /ID# 233179, Beijing

102206

Peking University International Hospital /ID# 232254, Beijing

215006

The First Affiliated Hospital of Soochow University /ID# 232418, Suzhou

300020

Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sc /ID# 232253, Tianjin

325000

The First Affiliated Hospital of Wenzhou Medical University /ID# 233704, Wenzhou

330006

The First Affiliated Hospital of Nanchang University /ID# 231442, Nanchang

430022

Union Hospital Tongji Medical College Huazhong University of Science and Technol /ID# 233178, Wuhan

441106

Xiangyang Central Hospital /ID# 232452, Xiangyang

450003

People's Hospital of Henan Province /ID# 232568, Zhengzhou

450008

Henan Cancer Hospital /ID# 231940, Zhengzhou

510060

Sun Yat-Sen University Cancer Center /ID# 231793, Guangzhou

510280

Zhujiang Hospital of Southern Medical University /ID# 231792, Guangzhou

510310

Guangdong Second Provincial General Hospital /ID# 232059, Guangzhou

510515

Nanfang Hospital of Southern Medical University /ID# 231938, Guangzhou

518039

Shenzhen Second People's Hospital /ID# 231444, Shenzhen

550002

Duplicate_The Affiliated Hospital of Guizhou Medical University /ID# 232465, Guiyang

644099

The Second People's Hospital of Yibin /ID# 233180, Yibin

810001

Qinghai University Affiliated Hospital /ID# 232419, Xining

Sponsors

Lead Sponsor

Collaborators (1)

All Listed Sponsors
collaborator

Genentech, Inc.

INDUSTRY

lead

AbbVie

INDUSTRY