Impact of Silymarin Dosages to Decrease Drug-induced Elevated Liver Enzymes Compared to Placebo

PHASE2/PHASE3SuspendedINTERVENTIONAL
Enrollment

156

Participants

Timeline

Start Date

June 23, 2021

Primary Completion Date

December 31, 2024

Study Completion Date

December 31, 2024

Conditions
Drug-induced Liver Injury
Interventions
DRUG

Placebo

1 capsule per day of placebo

DRUG

2x 140 mg per day

2 capsule per day of silimarit

DRUG

3x 280 mg per day

3 capsule per day of silimarit

DRUG

1x 1120 mg

8 capsule per day of silimarit

Trial Locations (2)

60590

Universtity Hospital - clinic for dermatology, venerology and allergology, Frankfurt

60596

CIRI, Frankfurt

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Bionorica SE

INDUSTRY

lead

Dr. Frank Behrens

OTHER