Hemostasis and Inflammation in COVID-19 Patients With Venous and Arterial Thrombotic Complications

NACompletedINTERVENTIONAL
Enrollment

150

Participants

Timeline

Start Date

November 1, 2021

Primary Completion Date

July 23, 2023

Study Completion Date

July 23, 2023

Conditions
Venous Thromboembolismcovid19Thrombosis
Interventions
OTHER

standard of care anticoagulation in absence of thrombotic complications

Subgroup IA - patients receive UFH (heparin, 7500 Units 2-3 times daily) for the prevention or treatment of VTE Subgroup IB - patients receive LMWH (enoxaparin) for the prevention or treatment of VTE Subgroup IC - patients receive oral anticoagulants (rivaroxaban 10mg QD) for the prevention or treatment of VTE

OTHER

standard of care anticoagulation in presence of thrombotic complications

Subgroup IIA - patients receive UFH (heparin, 7500 Units 2-3 times daily) for the prevention or treatment of VTE Subgroup IIB - patients receive LMWH (enoxaparin, 0.4ml 2 times daily) for the prevention or treatment of VTE Subgroup IIC - patients receive oral anticoagulants (rivaroxaban 10mg QD) for the prevention or treatment of VTE

OTHER

standard of care anticoagulation in combination with elastic compression

Subgroup IIIA - patients receive UFH (heparin, 7500 Units 2-3 times daily) in combination with class II elastic compression (compression stockings above the level of the knee) for the prevention or treatment of VTE Subgroup IIIB - patients receive LMWH (enoxaparin, 0.4ml 2 times daily) in combination with class II elastic compression (compression stockings above the level of the knee) for the prevention or treatment of VTE Subgroup IIIC - patients receive oral anticoagulants (rivaroxaban 10mg QD) in combination with class II elastic compression (compression stockings above the level of the knee) for the prevention or treatment of VTE

Trial Locations (1)

390026

Ryazan State Medical University, Ryazan

All Listed Sponsors
lead

Ryazan State Medical University

OTHER