Study to Compare Feasibility of 1-step Injectable Artesunate vs. Conventional 2-step Injectable Artesunate

PHASE2CompletedINTERVENTIONAL
Enrollment

200

Participants

Timeline

Start Date

July 18, 2022

Primary Completion Date

July 29, 2022

Study Completion Date

August 11, 2023

Conditions
Severe Malaria
Interventions
DRUG

Argesun 60mg (1 step parenteral artesunate)

Each vial of powder contains 60mg artesunate. Each ampoule of 6 ml solvent contains: sodium bicarbonate 8.4mg/ml; arginine 20mg/ml.

DRUG

Artesun 60mg (2-step parenteral artesunate)

Each vial of powder contains 60 mg artesunate. Each ampoule of 1 ml solvent contains 50 mg sodium bicarbonate. Each ampoule of 5 ml diluent contains 45 mg sodium chloride.

Trial Locations (1)

8502

KIMORU (KIMORU /ESP Research Center), Kinshasa

All Listed Sponsors
collaborator

Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd.

INDUSTRY

collaborator

University of Kinshasa

OTHER

collaborator

National Institute for Medical Research, Tanzania

OTHER_GOV

lead

University of Oxford

OTHER