A Drug-Drug Interaction Study Between ATI-2173 and Tenofovir Disoproxil Fumarate in Healthy Subjects

PHASE1CompletedINTERVENTIONAL
Enrollment

32

Participants

Timeline

Start Date

October 27, 2021

Primary Completion Date

December 23, 2021

Study Completion Date

December 23, 2021

Conditions
Drug Interaction
Interventions
DRUG

ATI-2173 50 mg

ATI-2173 is a liver-targeted phosphoramidate oral prodrug of clevudine designed to enhance anti-HBV activity while decreasing systemic exposure to clevudine. It will be dosed as a capsule by mouth

DRUG

Tenofovir 300Mg Oral Tablet

Tenofovir is an oral nucleotide analogue reverse transcriptase inhibitor used for chronic hepatitis B virus. It will be dosed as a tablet by mouth

Trial Locations (1)

H3P 3P1

Altasciences, Montreal

Sponsors
All Listed Sponsors
lead

Antios Therapeutics, Inc

INDUSTRY

NCT05137548 - A Drug-Drug Interaction Study Between ATI-2173 and Tenofovir Disoproxil Fumarate in Healthy Subjects | Biotech Hunter | Biotech Hunter