NCT05133817 - Prophylactic Norepinephrine Infusion Combined With Colloid Coloading for Postspinal Anesthesia Hypotension | Biotech Hunter

Enrollment

175

Participants

Timeline

Start Date

November 26, 2021

Primary Completion Date

September 3, 2022

Study Completion Date

September 3, 2022

Conditions

Adverse Event

Interventions

DRUG

Normal saline

Simultaneous with spinal anesthesia, 500 mL 6% Hydroxyethyl starch (130/0.4) coload was given and a maintenance dose of normal saline by IV infusion.

DRUG

Norepinephrine (0.025 μg/kg/min)

Simultaneous with spinal anesthesia, 500 mL 6% Hydroxyethyl starch (130/0.4) coload was given and a different maintenance dose of norepinephrine by IV infusion.

DRUG

Norepinephrine (0.05 μg/kg/min)

Simultaneous with spinal anesthesia, 500 mL 6% Hydroxyethyl starch (130/0.4) coload was given and a different maintenance dose of norepinephrine by IV infusion.

DRUG

Norepinephrine (0.075 μg/kg/min)

Simultaneous with spinal anesthesia, 500 mL 6% Hydroxyethyl starch (130/0.4) coload was given and a different maintenance dose of norepinephrine by IV infusion.

DRUG

Norepinephrine (0.1 μg/kg/min)

Simultaneous with spinal anesthesia, 500 mL 6% Hydroxyethyl starch (130/0.4) coload was given and a different maintenance dose of norepinephrine by IV infusion.

Trial Locations (1)

75004

General Hospital of Ningxia Medical University, Yinchuan

All Listed Sponsors

lead

General Hospital of Ningxia Medical University

OTHER