30
Participants
Start Date
June 20, 2022
Primary Completion Date
October 15, 2024
Study Completion Date
October 15, 2024
Clinical examination
The investigator will conduct a clinical examination to rule out other causes of olfactory impairment independent of COVID-19. The investigator will also collect the following information: socio-demographic data (age, sex, blood type, weight, height, etc.), history of olfaction disorder symptoms, past or current treatments received and tobacco/alcohol consumption.
Blood collection
12ml-blood sample
Olfactory evoked potentials
Olfactory evoked potentials will be recorded during olfactory tests.
Brushing of olfactory slits
collection of olfactory slits cells.
Neurological examination and neuropsychological assessment
"* MOCA, BREF~* CVLT~* WAIS IV, MEM III~* Right-side and left-side empan, Trail Making Test A and B (TMT), verbal fluency tests, PASAT, Attention Assessment Test~* Benton's Line Judgement, VOSP~* Assessment of psychological status, fatigue and screening for psychiatric comorbidities: depression \& anxiety scales (HAD scale, mADRS depression scale, STAI anxiety scale), Fatigue Severity Scale."
Nasal endoscopy
Nasal endoscopy
Assessment of olfactory and taste functions
"* scales: VAS and TSS~* Sniffin Stick test"
Hôpital Lariboisière, Paris
Lead Sponsor
Hopital Lariboisière
OTHER
Institut Pasteur
INDUSTRY