A Repeatability Study of Fatty Acid Uptake Using PET/MR Imaging in Patients With T2DM and Non-diabetic Control Subjects

NACompletedINTERVENTIONAL
Enrollment

19

Participants

Timeline

Start Date

March 29, 2021

Primary Completion Date

November 25, 2021

Study Completion Date

April 30, 2022

Conditions
Diabetes Mellitus, Type 2
Interventions
OTHER

Imaging Biomarkers

"One arm: Subjects are studied under two consecutive conditions, after overnight fasting and after a liquid meal ingestion. During each condition they are examined for fatty acid uptake in subcutaneous fat and skeletal muscle by FTHA(\[18F\]-FTHA) PET/MRI as well as adipose and skeletal muscle blood perfusion by radioactive water(\[15O\]-H2O ) PET/MRI. This was done at two occasions, 2-14 days apart, to assess repeatability of the measurements.~Assigned interventions:~\[18F\]-FTHA tracer injections \[15O\]-H2O tracer injections~PET/MRI imaging~Overnight fasting Liquid meal ingestion"

Trial Locations (2)

20520

Turku PET Centre, Turku

20521

Turku PET Centre (Turku University Hospital), Turku

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Antaros Medical

INDUSTRY

lead

Turku University Hospital

OTHER_GOV

NCT05132335 - A Repeatability Study of Fatty Acid Uptake Using PET/MR Imaging in Patients With T2DM and Non-diabetic Control Subjects | Biotech Hunter | Biotech Hunter