NCT05123326View on ClinicalTrials.gov

Global Coagulation Assessment in Portal Vein Thrombosis and Budd-Chiari Syndrome

RecruitingOBSERVATIONAL
Enrollment

300

Participants

Timeline

Start Date

October 15, 2021

Primary Completion Date

October 15, 2024

Study Completion Date

October 15, 2024

Conditions
Hepatic Vein ThrombosesHepatic Venous Outflow ObstructionPortal Vein ThrombosisPortal Hypertension, NoncirrhoticPortal Vein OcclusionPortal Vein EmbolismJAK2 MutationCALR Gene MutationProthrombin G20210AAnticoagulants and Bleeding Disorders
Interventions
DIAGNOSTIC_TEST

Rotational thromboelastometry

ROTEM/ Sonoclot tests will be done in all patients at enrolment and after initiating anticoagulation in those who are eligible for the same.

DIAGNOSTIC_TEST

Genetic tests for Thrombophilia

Tests for JAK2 mutation, CAL R mutation and Factor V Leiden mutation will be done.

DIAGNOSTIC_TEST

ELISA tests/ Functional assays

Antithrombin III, Protein C, Protein S, Factor VIII, VWF using commercial assays

Trial Locations (1)

160012

RECRUITING

Postgraduate Institute of Medical Education and Research, Chandigarh

All Listed Sponsors
lead

Post Graduate Institute of Medical Education and Research, Chandigarh

OTHER