BCX9930 for the Treatment of Paroxysmal Nocturnal Hemoglobinuria (PNH) in Participants With Inadequate Response to C5 Inhibitor Therapy

PHASE2TerminatedINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

December 6, 2021

Primary Completion Date

September 14, 2023

Study Completion Date

September 14, 2023

Conditions
Paroxysmal Nocturnal Hemoglobinuria (PNH)
Interventions
DRUG

Eculizumab

Administered by intravenous infusion per current dose regimen

DRUG

Ravulizumab

Administered by intravenous infusion per current dose regimen

DRUG

BCX9930

Administered orally twice daily

Trial Locations (7)

Unknown

Investigative Site, Paris

Investigative Site, Budapest

Investigative Site, Rome

Investigative Site, Barcelona

Investigative Site, Valencia

Investigative Site, Leeds

Investigative Site, London

Sponsors
All Listed Sponsors
lead

BioCryst Pharmaceuticals

INDUSTRY

NCT05116774 - BCX9930 for the Treatment of Paroxysmal Nocturnal Hemoglobinuria (PNH) in Participants With Inadequate Response to C5 Inhibitor Therapy | Biotech Hunter | Biotech Hunter