Off-the-shelf NK Cells + SCT for Myeloid Malignancies

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

April 8, 2022

Primary Completion Date

May 15, 2025

Study Completion Date

May 15, 2025

Conditions
Myeloid MalignanciesAcute Myeloid LeukemiaMyelodysplastic SyndromeChronic Myeloid Leukemia
Interventions
DRUG

Cyclophosphamide

Given by IV

DRUG

Mesna

Given by IV

DRUG

Filgrastim

Given by IV

DRUG

Melphalan

Given by IV

DRUG

Fludarabine phosphate

Given by IV

DRUG

Tacrolimus

Given by IV

DRUG

Mycophenolate mofetil

Given by IV

DRUG

Total Body Irradiation One Dose

Given by IV

Trial Locations (1)

77030

M D Anderson Caner Center, Houston

All Listed Sponsors
lead

M.D. Anderson Cancer Center

OTHER