Neoadjuvant and Adjuvant Lenvatinib in HCC Patients Treated by Percutaneous Ablative

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

32

Participants

Timeline

Start Date

February 2, 2022

Primary Completion Date

July 2, 2025

Study Completion Date

October 2, 2026

Conditions
Hepatocellular Carcinoma
Interventions
DRUG

Lenvatinib Pill

"The design of study is summarized as follows:~* Neoadjuvant phase with lenvatinib for 21 days (rationale: compromise between expected benefit and acceptable tolerance without compromising ablation procedure)~* PA of HCC in a curative intent (radiofrequency, microwave or electroporation)~* Adjuvant phase with lenvatinib for 3 months (rationale: compromise between expected benefit and acceptable tolerance without compromising ablation procedure)"

Trial Locations (1)

93000

NAHON, Bobigny

All Listed Sponsors
collaborator

Eisai Inc.

INDUSTRY

lead

Assistance Publique - Hôpitaux de Paris

OTHER