Does Repeat Influenza Vaccination Constrain Influenza Immune Responses and Protection

Active, not recruitingOBSERVATIONAL
Enrollment

1,500

Participants

Timeline

Start Date

April 2, 2020

Primary Completion Date

June 30, 2025

Study Completion Date

June 30, 2025

Conditions
Influenza, HumanSARS-CoV-2 Infection
Interventions
BIOLOGICAL

Influenza vaccination: Fluarix Tetra, Vaxigrip Tetra, Fluquadri, Fluad Quad, Afluia Quad, Flucelvax Quad

Influenza vaccine made available to healthcare workers at the participating healthcare sites, as part of their free vaccination campaigns for healthcare workers.

BIOLOGICAL

SARS-CoV-2 vaccination: Comirnaty or Vaxzevria

SARS-CoV-2 vaccine made available to healthcare workers at the participating healthcare sites, as part of their free vaccination campaigns for healthcare workers.

Trial Locations (6)

2145

The Children's Hospital at Westmead, Westmead

2305

John Hunter Hospital, New Lambton Heights

3004

The Alfred, Melbourne

4101

Queensland Children's Hospital, Brisbane

5006

Women's and Children's Hospital, Adelaide

6009

Perth Children's Hospital, Nedlands

All Listed Sponsors
collaborator

The University of Queensland

OTHER

collaborator

Sydney Children's Hospitals Network

OTHER

collaborator

The Alfred

OTHER

collaborator

University of Adelaide

OTHER

collaborator

The University of Western Australia

OTHER

collaborator

London School of Hygiene and Tropical Medicine

OTHER

collaborator

University of Newcastle, Australia

OTHER

lead

University of Melbourne

OTHER