Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain Cancer

Ibrutinib will be taken by mouth once daily, on days 1-21 of each treatment cycle.

Indoximod will be taken by mouth twice daily, throughout each treatment cycle.

Cyclophosphamide will be taken by mouth once daily, on days 1-21 of each treatment cycle.

Etoposide will be taken by mouth once daily, on days 1-21 of each treatment cycle.