Camrelizumab for the Treatment of Locally Advanced Nasopharyngeal Carcinoma

PHASE2RecruitingINTERVENTIONAL
Enrollment

200

Participants

Timeline

Start Date

April 6, 2022

Primary Completion Date

April 6, 2025

Study Completion Date

April 6, 2026

Conditions
Nasopharyngeal Carcinoma
Interventions
DRUG

Camrelizumab

Camrelizumab 200mg will be given every 3 weeks for 3 cycles started on day 1 of induction chemotherapy and every 2 weeks for 9 cycles thereafter.

DRUG

Gemcitabine

Gemcitabine 1g/m2, d1 \& 8 of every cycle, every 3 weeks for 3 cycles before radiation

DRUG

Induction Cisplatin

Induction cisplatin 80mg/m2, every 3 weeks for 3 cycles before radiation

RADIATION

intensity-modulated radiotherapy

Definitive intensity-modulated radiotherapy (IMRT) of 6996cGy will be given in 33 fractions.

DRUG

Concurrent cisplatin

Concurrent cisplatin 100mg/m2, every 3 weeks for 2 cycles during radiation

Trial Locations (5)

Unknown

RECRUITING

Guangxi Nanxishan hospital, Guilin

RECRUITING

Guilin Medical University, Guilin

RECRUITING

Laibin People's Hospital, Laibin

RECRUITING

Linshan people's hospital, Linshan

NOT_YET_RECRUITING

Wuzhou Red Cross Hospital, Wuzhou

All Listed Sponsors
collaborator

Wuzhou Red Cross Hospital

OTHER

collaborator

Guangxi Nanxishan Hospital

UNKNOWN

collaborator

Laibin People's Hospital

OTHER

collaborator

Lingshan people's Hospital

UNKNOWN

lead

Wei Jiang

OTHER