Blood-Stage Plasmodium Vivax Cell Bank

PHASE1CompletedINTERVENTIONAL
Enrollment

2

Participants

Timeline

Start Date

February 15, 2022

Primary Completion Date

June 24, 2022

Study Completion Date

September 15, 2022

Conditions
Malaria
Interventions
BIOLOGICAL

HMPBS02-Pv

The blood-stage P. vivax master cell bank HMPBS02-Pv was also produced using blood collected from a consenting patient with naturally acquired malaria infection. The malaria infection was confirmed to be P. vivax by species-specific PCR at Pathology Queensland (accredited by the Australian National Association of Testing Authorities) and further confirmed by deep sequencing at the Sanger Institute. The clinical response to antimalarial chemotherapy was also demonstrated with this donor, who was successfully cured with artemether/lumefantrine.

Trial Locations (1)

20892

National Institutes of Health Clinical Center, Bethesda

All Listed Sponsors
lead

National Institute of Allergy and Infectious Diseases (NIAID)

NIH