NCT05093959View on ClinicalTrials.gov

Metformin for Older Patients With Heart Failure With Preserved Ejection Fraction

PHASE2Active, not recruitingINTERVENTIONAL
Enrollment

86

Participants

Timeline

Start Date

January 4, 2022

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
Heart Failure With Preserved Ejection Fraction
Interventions
DRUG

Metformin

An extended release formulation will be used which improves compliance and reduces GI side effects.

DRUG

Placebo

Placebo is a biologically inert substance placed in capsules to match appearance of active intervention

Trial Locations (2)

27157

Wake Forest School of Medicine, Winston-Salem

28203

Atrium Health Sanger Heart and Vascular Clinic Institute, Charlotte

All Listed Sponsors
collaborator

University of South Florida

OTHER

collaborator

National Institute on Aging (NIA)

NIH

lead

Wake Forest University Health Sciences

OTHER