Cannabis as a Complementary Treatment in Multiple Sclerosis

PHASE2RecruitingINTERVENTIONAL
Enrollment

250

Participants

Timeline

Start Date

November 10, 2022

Primary Completion Date

April 10, 2025

Study Completion Date

May 10, 2025

Conditions
Multiple Sclerosis
Interventions
DRUG

Cannabis oil vs placebo

"Eligibility, Screening and Baseline (T0):~Candidates will be seen by both research staff and a neurologist. Full written informed consent will be obtained before completing questionnaires and administering physical and medical evaluations. If eligibility is confirmed, a blood sample will be collected followed by participant randomisation .~Follow-up visits:~Randomized participants come back after 4 weeks (T1) for the same assessments administered at T0. Only participants who had a decrease in their level of spasticity can continue their participation in the same allocated arm for an additional period of 12 weeks.~At the end of the additional period of 12 weeks (T2), another visit is scheduled for a last assessments which are the same as T0 and T1.~Throughout study, courtesy calls will be scheduled and standard care for MS will also be offered to ensure participants 'safety and well-being."

Trial Locations (1)

H2X 0A9

RECRUITING

CRCHUM, Montreal

All Listed Sponsors
collaborator

Canadian Institutes of Health Research (CIHR)

OTHER_GOV

collaborator

Multiple Sclerosis Society of Canada

OTHER

lead

Centre hospitalier de l'Université de Montréal (CHUM)

OTHER