The Optimal Long Term Treatment Strategy of Anti-resorptive Medications

PHASE4Active, not recruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

November 20, 2021

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2030

Conditions
OsteoporosisBone Mineral Density
Interventions
DRUG

Continuous Denosumab

Active comparator: persistent treatment of denosumab.

DRUG

Administer zoledronate and denosumab on an alternating schedule

In the experimental group, zoledronic acid was administered for one year, followed by two years of denosumab. This cycle was repeated, with the regimen concluding with one year of zoledronic acid.

Trial Locations (1)

640

National Taiwan University Hospital, Yunlin branch, Douliu

All Listed Sponsors
lead

National Taiwan University Hospital

OTHER