Efficacy of Prolonged Anticoagulation for Primary Prevention of Venous Thromboembolic Disease in Autoimmune Hemolytic Anemia: a Prospective, Phase II, Randomized, Multicenter Study

PHASE2RecruitingINTERVENTIONAL
Enrollment

72

Participants

Timeline

Start Date

February 3, 2022

Primary Completion Date

August 31, 2028

Study Completion Date

August 31, 2028

Conditions
Prolonged AnticoagulationVenous Thromboembolic DiseaseAutoimmune Hemolytic Anemia
Interventions
DRUG

"treatment intervention"

for a total of 12 weeks, prophylactic heparin therapy during hospitalization followed by prophylactic oral anticoagulation with apixaban

DRUG

"treatment standard"

during hospitalization prophylactic heparin therapy followed by management without prophylactic anticoagulation.

BIOLOGICAL

biological assessment

CBC, reticulocytes, haptoglobin, LDH, bilirubin

Trial Locations (1)

21000

RECRUITING

Chu Dijon Bourgogne, Dijon

All Listed Sponsors
lead

Centre Hospitalier Universitaire Dijon

OTHER