MULTIple Doses of IPTi Proposal: a Lifesaving High Yield Intervention

Active, not recruitingOBSERVATIONAL
Enrollment

94,252

Participants

Timeline

Start Date

February 14, 2022

Primary Completion Date

December 31, 2024

Study Completion Date

October 31, 2025

Conditions
Malaria
Interventions
DRUG

Intermittent preventive treatment of malaria in infants (IPTi) with sulfadoxine-pyrimethamine (SP)

IPTi will be administered as full therapeutic courses of SP alongside routine EPI immunisations at defined intervals corresponding to vaccination schedules - usually at 10 weeks, 14 weeks, and 9 months of age - to infants living in project districts. Additional doses of IPTi will be administered at 6, 12, and 15 or 18 months of age, coinciding with vitamin A administration and measles booster immunisation. The number of doses of IPTi a child will receive will depend of the EPI schedule in the country, with a maximum of six doses in the first two years of life.

Trial Locations (3)

Unknown

Fundaçao Manhiça, Manhiça

College of Medicine & Allied Health Sciences (COMAHS), University of Sierra Leone, Freetown

University of Lomé, Lomé

All Listed Sponsors
collaborator

Institut de Recherche pour le Developpement

OTHER_GOV

collaborator

Centro de Investigação em Saúde de Manhiça

OTHER

collaborator

Medicines for Malaria Venture

OTHER

collaborator

University of Lomé (UL), Togo

UNKNOWN

collaborator

University of Sierra Leone

OTHER

lead

Barcelona Institute for Global Health

OTHER