NCT05084378View on ClinicalTrials.gov

Evaluation of Emerging New Treatments for Infection Prevention in Total Joint Replacement

PHASE3CompletedINTERVENTIONAL
Enrollment

495

Participants

Timeline

Start Date

March 11, 2022

Primary Completion Date

August 4, 2024

Study Completion Date

October 28, 2024

Conditions
Periprosthetic Joint InfectionDraining Wound
Interventions
DRUG

Povidone-Iodine Lavage Solution

0.35% povidone-iodine solution mixed with 1 litre of sterile isotonic saline solution. Commercially available products with 0.35% povidone-iodine and sterile isotonic saline solution may also be used.

DRUG

Chlorhexidine Lavage Solution

0.05% chlorhexidine solution mixed with 1 litre of sterile isotonic saline solution. Commercially available products with 0.05% chlorhexidine and sterile isotonic saline may also be used.

DRUG

Topical Antibiotic

2 grams Vancomycin powder

DRUG

Saline Lavage Solution

1 litre of sterile isotonic saline

Trial Locations (6)

L8N4A6

St. Joseph's Healthcare, Hamilton

L8V 1C3

Hamilton Health Sciences- Juravinkski Hospital, Hamilton

Unknown

Montreal General Hospital, Montreal

St. Mary's Hospital, Montreal

Hospital Clinic Barcelona, Barcelona

Vall d'Hebron University Hospital, Barcelona

All Listed Sponsors
collaborator

McMaster University

OTHER

lead

Hamilton Health Sciences Corporation

OTHER