Neoadjuvant Personalized Anti-PD-1 and Anti-VEGFR Therapy in OSCC Patients

PHASE2RecruitingINTERVENTIONAL
Enrollment

46

Participants

Timeline

Start Date

September 1, 2021

Primary Completion Date

August 30, 2024

Study Completion Date

June 30, 2028

Conditions
Oral Squamous Cell CarcinomaNeoadjvant TherapyAnti-PD-1Anti-VEGFR
Interventions
DRUG

Camrelizumab (anti-PD-1 inhibitor)

The patients will receive three cycles of Camrelizumab, with 14 days each. 200mg of Carrelizumab will be used intravenously on the first day of each cycle.

DRUG

Apatinib (anti-VEGFR inhibitor)

The patients will receive Apatinib orally 250mg once a day from the first day of each cycle until the 9th day of the third cycle.

Trial Locations (1)

20011

RECRUITING

Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai

All Listed Sponsors
lead

Shanghai Jiao Tong University School of Medicine

OTHER

NCT05069857 - Neoadjuvant Personalized Anti-PD-1 and Anti-VEGFR Therapy in OSCC Patients | Biotech Hunter | Biotech Hunter