Treatment of CD79B Mutant Relapsed/Refractory Diffuse Large B-Cell Lymphoma With Bruton Tyrosine Kinase Inhibitor Zanubrutinib

PHASE2CompletedINTERVENTIONAL
Enrollment

65

Participants

Timeline

Start Date

August 11, 2021

Primary Completion Date

March 31, 2025

Study Completion Date

March 31, 2025

Conditions
Relapsed Diffuse Large B-cell LymphomaRefractory Diffuse Large B-cell Lymphoma
Interventions
DRUG

Zanubrutinib

administered orally as capsules

Trial Locations (25)

100050

Beijing Friendship Hospital, Capital Medical University, Beijing

110042

Liaoning Cancer Hospital and Institute, Shenyang

130021

The First Hospital of Jilin University, Changchun

150000

Harbin Medical University Cancer Hospital, Harbin

200025

Rui Jin Hospital Shanghai Jiao Tong University School of Medicine, Shanghai

230088

Anhui Provincial Cancer Hospital Aka West Branch of Anhui Province Hospital, Hefei

300020

Institute of Hematology and Hospital of Blood Disease, Tianjin

310003

The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou

310009

Zhejiang University College of Medicine Second Affiliated Hospital, Hangzhou

317000

Taizhou Hospital of Zhejiang, Taizhou

330006

The First Affiliated Hospital of Nanchang University Branch Donghu, Nanchang

350014

Fujian Cancer Hospital, Fuzhou

410011

The Second Xiangya Hospital of Central South University, Changsha

410013

Hunan Cancer Hospital, Changsha

430022

Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan

430030

Tongji Hospital of Tongji Medical College Huazhong University of Science and Technology, Wuhan

450000

Henan Cancer Hospital, Zhengzhou

510060

Sun Yat Sen University Cancer Center, Guangzhou

510120

Guangdong Provincial Peoples Hospital Huifu Branch, Guangzhou

The First Affiliated Hospital of Guangzhou Medical University, Guangzhou

515041

The First Affiliated Hospital of Shantou University Medical College, Shantou

570312

Hainan Cancer Hospital, Haikou

610041

West China Hospital, Sichuan University, Chengdu

650100

Yunnan Cancer Hospital, Kunming

030013

Shanxi Provincial Cancer Hospital, Taiyuan

Sponsors

Lead Sponsor

All Listed Sponsors
lead

BeiGene

INDUSTRY