NCT05067595View on ClinicalTrials.gov

Fecal Microbiota Transplant and Dietary Fiber Supplementation for the Treatment of Gut Graft Versus Host Disease

PHASE1RecruitingINTERVENTIONAL
Enrollment

72

Participants

Timeline

Start Date

January 24, 2025

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
Intestinal Graft Versus Host Disease
Interventions
PROCEDURE

Colonoscopy

Undergo lower FMT via colonoscopy

BIOLOGICAL

Fecal Microbiota Transplantation

Given upper FMT PO or via post-pyloric or NG feeding tube

BIOLOGICAL

Fecal Microbiota Transplantation

Undergo lower FMT via colonoscopy

DIETARY_SUPPLEMENT

Nutritional Supplementation

Given dietary fiber supplementation PO or via post-pyloric or NG feeding tube

OTHER

Survey Administration

Ancillary studies

PROCEDURE

Biospecimen Collection

Undergo tissue, stool, stool swabs, and blood sample collection

Trial Locations (1)

98109

RECRUITING

Fred Hutch/University of Washington Cancer Consortium, Seattle

All Listed Sponsors
collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH

lead

Fred Hutchinson Cancer Center

OTHER