A Study to Evaluate the Efficacy and Safety of Intravitreal KSI-301 in Non-proliferative Diabetic Retinopathy (NPDR)

PHASE3TerminatedINTERVENTIONAL
Enrollment

253

Participants

Timeline

Start Date

September 7, 2021

Primary Completion Date

August 3, 2023

Study Completion Date

August 31, 2023

Conditions
Non-proliferative Diabetic Retinopathy
Interventions
DRUG

KSI-301

Intravitreal injection

OTHER

Sham injection

The sham injection is a procedure that mimics an intravitreal injection. It involves pressing the blunt end of an empty syringe (without a needle) against the anesthetized eye. It is performed to maintain masking of the study.

Trial Locations (61)

11572

Ophthalmic Consultants of Long Island, Oceanside

11788

Long Island Vitreoretinal Consultants, Hauppauge

21740

Cumberland Valley Retina Consultants PC, Hagerstown

24502

Piedmont Eye Center, Lynchburg

28220

Hospital Universitario Puerta de Hierro - Majadahonda, Madrid

29414

Charleston Neuroscience Center, Charleston

29902

Charleston Neurosciences Institute, Beaufort

30909

Southeast Retina Center, Augusta

32806

Florida Retina Institute, Orlando

32901

Florida Eye Associates, Melbourne

33143

Med Eye Associates, Miami

33308

Retina Group of Florida, Fort Lauderdale

33761

The Macula Center/ Blue Ocean Clinical Research, Clearwater

33880

Center for Retina & Macular Disease, Winter Haven

37203

Tennessee Retina PC, Nashville

37909

Southeastern Retina Associates PC, Knoxville

49525

Foundation for Vision Research, Grand Rapids

50001

Hospital Clinico Universitario Lozano Blesa, Zaragoza

50006

Hospital Universitario Miguel Servet, Zaragoza

60637

University of Chicago, Chicago

62703

Springfield Clinic LLP, Springfield

66215

Retina Associates PA, Lenexa

75075

Texas Retina Associates, Plano

76028

Star Vision Consultants, Burleson

77384

Retina Consultants of Texas - (Woodlands), The Woodlands

77401

Retina Consultants of Texas (Houston), Bellaire

77494

Retina Consultants of Texas (Katy), Katy

78240

Medical Center Ophthalmology Associates, San Antonio

Retina Consultants of San Antonio, San Antonio

78681

Austin Retina Associates (Round Rock), Round Rock

78705

Austin Retina Associates, Austin

79106

Panhandle Eye Group, LLP, Amarillo

79606

Retina Research Institute of Texas, Abilene

83713

Retina Specialists of Idaho, Boise

85014

Retinal Research Institute, LLC, Phoenix

89502

Sierra Eye Associates, Reno

90211

Retina Vitreous Associates, Beverly Hills

92374

Retina Consultants of Southern California, Redlands

92835

Retina Consultants of Orange County, Fullerton

93454

California Retina Consultants - Santa Maria, Santa Maria

95825

Retinal Consultants Medical Group Inc, Sacramento

97401

Cascade Medical Research Institute, Eugene

99204

Spokane Eye, Spokane

06810

Connecticut Eye Consultants, Danbury

06385

Retina Group of New England, Waterford

07003

Envision Ocular LLC, Bloomfield

28603-2588

Graystone Eye, Hickory

18017-9412

MidAtlantic Retina, Bethlehem

38119-4823

Charles Retina Institute, Memphis

530 02

OFTEX s.r.o., Pardubice

15 0 00

Axon Clinical, s.r.o., Prague

LV-1002

Pauls Stradins Clinical University Hospital, Riga

LV-1009

Latvian American Eye Center, Riga

01-258

Warszawski Szpital Okulistyczny, Warsaw

80-952

Optimum Profesorskie Centrum Okulistyki, Gdansk

85-631

Oftalmika Sp. z o.o., Bydgoszcz

00612

Emanuelli Research & Development Center LLC, Arecibo

975 17

Fakultna nemocnica s poliklinikou F. D. Roosevelta, Banská Bystrica

911 71

Fakultna nemocnica Trencin, Trenčín

08907

Hospital Universitario de Bellvitge, L'Hospitalet de Llobregat

08195

Hospital Universitari General de Catalunya - Grupo Quironsalud, Sant Cugat del Vallès

Sponsors
All Listed Sponsors
lead

Kodiak Sciences Inc

INDUSTRY

NCT05066230 - A Study to Evaluate the Efficacy and Safety of Intravitreal KSI-301 in Non-proliferative Diabetic Retinopathy (NPDR) | Biotech Hunter | Biotech Hunter