ALTUS: Performance of a Multi- Target Hepatocellular Carcinoma (HCC) Test in Subjects With Increased Risk

Active, not recruitingOBSERVATIONAL
Enrollment

2,990

Participants

Timeline

Start Date

July 26, 2021

Primary Completion Date

September 12, 2025

Study Completion Date

December 31, 2026

Conditions
Hepatocellular CarcinomaHepatocellular CancerHepatitis BCirrhosisLiver Cancer
Interventions
DEVICE

Study CT/MRI Imaging

Subjects with negative ultrasound will be sent for a study CT/MRI.

DEVICE

Standard of Care CT/MRI Imaging

Subjects with positive ultrasound are anticipated to have standard of care imaging follow-up as well as other procedures as needed.

DIAGNOSTIC_TEST

Oncoguard™ Liver Test

Subjects will have a blood sample collected for the Oncoguard™ Liver Test.

Trial Locations (76)

10029

Icahn School of Medicine at Mount Sinai, New York

10279

Manhattan Clinical Research, LLC, New York

11209

Brooklyn VA Medical Center, Brooklyn

15213

University of Pittsburgh Medical Center, Pittsburgh

17011

Great Lakes Medical Research - Susquehanna Research Group, Camp Hill

18711

Wilkes-Barre VA Medical Center, Wilkes-Barre

19104

Corporal Michael J. Crescenz VA Medical Center, Philadelphia

University of Pennsylvania, Philadelphia

19107

Xiaoli MA MD, Philadelphia

19141

Einstein Medical Center, Philadelphia

20110

Gastroenterology Associates, PC, Manassas

20422

Washington DC VA Medical Center, Washington D.C.

21236

Patient First Clinical Trials, Nottingham

22903

UVA Gastroenterology, Charlottesville

23226

Bon Secours Liver Institute of Richmond, Richmond

23249

Richmond VA Medical Center, Richmond

23502

Digestive & Liver Disease Specialists, Norfolk

27710

Duke University Health Systems, Durham

28801

Digestive Health Partners, Asheville

29401

Ralph H Johnson VAMC, Charleston

32209

University of Florida - College of Medicine, Jacksonville

32256

ENCORE Borland Groover Clinical Research, Jacksonville

32610

University of Florida Hepatology Research at CTRB, Gainesville

33014

San Marcus Research Clinic, Miami Lakes

33125

Miami VA Healthcare System, Miami

33136

University of Miami, Miami

33606

Tampa General Hospital, Tampa Bay

34211

Florida Research Institute, Lakewood

38138

Gastro One, Germantown

39216

Southern Therapy and Advanced Research LLC (STAR), Jackson

44106

VA North East Ohio Health Care System, Cleveland

44195

Cleveland Clinic Foundation, Cleveland

46201

NAVREF - Indiana Institute for Medical Research (IIMC), Indianapolis

46202

Indiana University, Indianapolis

46237

Indianapolis Gastroenterology Research Foundation, Indianapolis

48109

University of Michigan, Ann Arbor

48202

Henry Ford Health System, Detroit

52242

University of Iowa Hospitals and Clinics, Iowa City

53705

UW Digestive Health Center, Madison

55902

Mayo Clinic Rochester, Rochester

60010

Gastroenterology and Internal Medicine Specialists, Lake Barrington

60026

Illinois Gastroenterology Group, Glenview

60031

GI Alliance of Illinois - Gurnee, Gurnee

60463

Avicenna Clinical Research, Oak Lawn

60515

Digestive Health Services, Downers Grove

63104

St. Louis University, St Louis

64128

Kansas City VA Medical Center, Kansas City

71105

Louisiana Research Center, LLC, Shreveport

71201

Delta Research Partners, Monroe

75390

UT Southwestern Medical Center, Dallas

77030

Baylor - Saint Luke's Medical Center, Houston

77598

Tranquil Clinical Research, Webster

78666

Texas Digestive Disease Consultants - San Marcos, San Marcos

79410

Lubbock Digestive Disease Associates, Lubbock

79936

Texas Gastro Clinic, El Paso

80120

Rocky Mountain Gastroenterology, Littleton

85225

Arizona Health Research, Chandler

85251

Arizona Digestive Health - Sun City, Sun City

90048

Cedars Sinai Medical Center, Los Angeles

91107

California Liver Research Institute, Pasadena

91345

Providence Facey Medical Foundation, Mission Hills

92025

Gastroenterology & Liver Institute, Escondido

92064

Cadena Care Institute, Poway

92105

Research & Education, Inc, San Diego

92377

Inland Empire Clinical Trials, Rialto

92563

United Medical Doctors, Murrieta

93301

Franco Felizarta, MD, Bakersfield

94303

VA Palo Alto Healthcare System, Palo Alto

94304

Stanford University Medical Center, Palo Alto

95128

San Jose Gastroenterology, San Jose

98056

Washington Gastroenterology - Bellevue, Bellevue

98101

Virginia Mason Medical Center, Seattle

98405

Washington Gastroenterology - Tacoma, Tacoma

99202

Velocity Clinical Research, Spokane

02904

University Gastroenterology West River, Providence

05401

University of Vermont Medical Center, Burlington

Sponsors
All Listed Sponsors
lead

Exact Sciences Corporation

INDUSTRY

NCT05064553 - ALTUS: Performance of a Multi- Target Hepatocellular Carcinoma (HCC) Test in Subjects With Increased Risk | Biotech Hunter | Biotech Hunter