Impact of Timing of Midazolam Administration on Incidence of Postoperative Nausea and Vomiting

NACompletedINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

September 10, 2021

Primary Completion Date

June 30, 2022

Study Completion Date

July 31, 2022

Conditions
Postoperative Nausea and Vomiting
Interventions
DRUG

Midazolam injection

No premedication will be given to Patients in the group undergoing a standardized anesthesia protocol which include induction with thiopental (5 mg/kg) and fentanyl (1-2 μg/kg). Atracurium will be used as a muscle relaxant. After tracheal intubation, anesthesia will be maintained with isoflurane in a concentration of 0.8%-1.2%. Ventilation will be adjusted to produce normocapnia. At the end of surgery, reversal of residual neuromuscular blockade will be accomplished using i.v. atropine 20 μg/Kg and neostigmine 40 μg/kg.

Trial Locations (1)

13511

Samar Rafik Mohamed Amin, Banhā

All Listed Sponsors
lead

Benha University

OTHER

NCT05057767 - Impact of Timing of Midazolam Administration on Incidence of Postoperative Nausea and Vomiting | Biotech Hunter | Biotech Hunter