Opportunistic PK/PD Trial in Critically Ill Children (OPTIC)

RecruitingOBSERVATIONAL
Enrollment

2,000

Participants

Timeline

Start Date

October 5, 2021

Primary Completion Date

October 30, 2025

Study Completion Date

October 30, 2026

Conditions
Cardiac DiseaseCritically IllChildren, Adult
Interventions
DRUG

The OPTIC study is collecting PK data on children prescribed understudied drugs of interest per standard of care.

The goal of this study is to characterize the pharmacokinetics of understudied drugs for which specific dosing recommendations and safety data are lacking. The prescribing of drugs to children will not be part of this protocol. Taking advantage of procedures done as part of routine medical care (i.e. blood draws), this study will serve as a tool to better understand drug exposure in children receiving these drugs per standard of care.

Trial Locations (1)

27705

RECRUITING

Duke University Medical Center, Durham

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

Food and Drug Administration (FDA)

FED

lead

Duke University

OTHER

NCT05055830 - Opportunistic PK/PD Trial in Critically Ill Children (OPTIC) | Biotech Hunter | Biotech Hunter