A Study to Evaluate the Durability of Response and Safety of Nemolizumab for 24 Weeks in Participants With Prurigo Nodularis

PHASE3CompletedINTERVENTIONAL
Enrollment

34

Participants

Timeline

Start Date

January 24, 2022

Primary Completion Date

September 11, 2023

Study Completion Date

September 11, 2023

Conditions
Prurigo Nodularis
Interventions
DRUG

Nemolizumab

Participants received either 1 \[30 milligram (mg)\] or 2 (2\*30 mg) subcutaneous (SC) injection(s) of nemolizumab every 4 weeks (Q4W) for a period of 24 weeks (with last injection at Week 20). Participants received the same dosage (1 or 2 SC injections) as received in the lead-in LTE study RD.06.SPR.202699, as assigned by interactive response technology (IRT).

DRUG

Placebo

Participants received either 1 (30 mg) or 2 (2\*30 mg) SC injection(s) of placebo every 4 weeks for a period of 24 weeks (with last injection at Week 20). Participants received the same dosage (1 or 2 SC injections) as received in the lead-in LTE study RD.06.SPR.202699, as assigned by IRT.

Trial Locations (14)

1011

Galderma Investigational Site 5069, Lausanne

1220

Galderma Investigational Site 6158, Vienna

8036

Galderma Investigational Site 5471, Graz

12203

Galderma Investigational Site 5604, Berlin

15355

Galderma Investigational Site 6098, Ansan

26000

Galderma Investigational Site 6168, Valence

29200

Galderma Investigational Site 5104, Brest

53127

Galderma Investigational Site 6082, Bonn

64506

Galderma Investigational Site 8521, Saint Joseph

69115

Galderma Investigational Site 6210, Heidelberg

06200

Galderma Investigational Site 5140, Nice

31-559

Galderma Investigational Site 6052, Krakow

27-400

Galderma Investigational Site 6237, Ostrowiec Świętokrzyski

35-055

Galderma Investigational Site 5495, Rzeszów

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Galderma R&D

INDUSTRY