104
Participants
Start Date
March 19, 2020
Primary Completion Date
September 30, 2023
Study Completion Date
September 30, 2024
Autologous Chondrocyte Implantation (CartiLife®)
CartiLife consists of small beads (1 mm in diameter) in suspension, developed from pellet culture of autologous costal chondrocytes after multiplication. The beads are implanted in an injective manner with fibrin glue through minimal arthrotomy. The dose depends on the size (volume) of the defect, recommended dose is 480 pellets/cm\^3 defect
Microfracture Surgery
Microfracture surgery, performed by arthroscopy after the joint is cleaned of calcified cartilage, will be conducted using an awl or drill to create tiny fractures in the subchondral bone plate
The Catholic UNIV. of Korea Uijeongbu St. Mary's Hospital, Uijeongbu-si
Seoul National University Bundang Hospital (1), Seongnam-si
Seoul National University Bundang Hospital (2), Seongnam-si
The Catholic UNIV. of Korea Seoul St. Mary's Hospital, Seoul
Chungnam National University Hospital, Daejeon
Pusan National University Hospital, Pusan
Inje University Haeundae Paik Hospital, Busan
Kosin University Gospel Hospital, Busan
Chonnam National University Hwasun Hospital, Gwangju
Chosun University Hospital, Gwangju
Kyung Hee University Hospital, Seoul
Seoul National University Hospital, Seoul
Severance Hospital, Seoul
Kyung Hee University Hospital at Gangdong, Seoul
Gangnam Severance Hospital, Seoul
Samsung Medical Center, Seoul
Ewha Womans University Mokdong Hospital, Seoul
Korea University Guro Hospital, Seoul
Lead Sponsor
Biosolution Co., Ltd.
INDUSTRY