A Study of Talquetamab With Other Anticancer Therapies in Participants With Multiple Myeloma

PHASE1Active, not recruitingINTERVENTIONAL
Enrollment

166

Participants

Timeline

Start Date

September 22, 2021

Primary Completion Date

March 31, 2025

Study Completion Date

April 7, 2027

Conditions
Multiple Myeloma
Interventions
DRUG

Talquetamab

Talquetamab will be administered subcutaneously.

DRUG

Carfilzomib

Carfilzomib will be administered as an IV infusion.

DRUG

Daratumumab SC

Daratumumab will be administered subcutaneously.

DRUG

Lenalidomide

Lenalidomide will be self-administered orally.

DRUG

Pomalidomide

Pomalidomide will be self-administered orally.

Trial Locations (31)

1200

Cliniques Universitaires St-Luc, Brussels

2500

Wollongong Hospital, Wollongong

2650

UZA, Edegem

3000

UZ Leuven, Leuven

3004

Alfred Health, Melbourne

3065

St Vincents Hospital Melbourne, Fitzroy

4215

Gold Coast University Hospital, Southport

9000

UZ Gent, Ghent

10029

Mt. Sinai School of Medicine, New York

10065

Weill Cornell Medical College, New York

15232

University of Pittsburgh Medical Center, Pittsburgh

28204

Levine Cancer Institute, Charlotte

30322

Emory University, Atlanta

31059

Institut Universitaire du cancer de Toulouse-Oncopole, Toulouse

33604

CHU de Bordeaux - Hospital Haut-Leveque, Pessac

35000

Chu Rennes Hopital Pontchaillou, Rennes

35294

University of Alabama Birmingham, Birmingham

37203

Tennessee Oncology, Nashville

44093

CHU Nantes, Nantes

46202

Indiana University, Indianapolis

53226

Medical College Of Wisconsin, Milwaukee

80218

Colorado Blood Cancer Institute, Denver

94143

University of California San Francisco, San Francisco

07601

Hackensack University Medical Center, Hackensack

9713 GZ

UMCG, Groningen

6229 HX

Maastricht University Medical Centre, Maastricht

3584 CX

UMCU, Utrecht

W1T 7HA

University College Hospital London, London

M20 4BX

The Christie Nhs Foundation Trust, Manchester

OX3 7LE

Churchill Hospital, Oxford

SM2 5PT

The Royal Marsden NHS Trust Sutton, Surrey

All Listed Sponsors
lead

Janssen Research & Development, LLC

INDUSTRY