ITIL-168 in Advanced Melanoma

PHASE2TerminatedINTERVENTIONAL
Enrollment

29

Participants

Timeline

Start Date

October 7, 2021

Primary Completion Date

February 27, 2023

Study Completion Date

February 27, 2023

Conditions
Advanced Cutaneous Melanoma
Interventions
BIOLOGICAL

ITIL-168

ITIL-168 is a cell therapy product derived from a patient's own TILs. A tumor sample is removed from each patient to make a personalized ITIL-168 product. Once ITIL-168 has been made, the patient is treated with 5 days of lymphodepleting chemotherapy including cyclophosphamide and fludarabine, followed by a single infusion of ITIL-168, and up to 8 doses of IL-2.

Trial Locations (22)

18015

St. Luke's University Health Network, Bethlehem

19111

Fox Chase Cancer Center, Philadelphia

20007

Georgetown University Medical Center, Washington D.C.

32806

Orlando Health Cancer Institute, Orlando

33136

The University of Miami - Sylvester Comprehensive Cancer Center, Miami

33612

Moffitt Cancer Center, Tampa

40202

University of Louisville, James Graham Brown Cancer Center, Louisville

44195

Cleveland Clinic - Taussig Cancer Center, Cleveland

55455

University of Minnesota, Masonic Cancer Center, Minneapolis

60153

Loyola University Chicago, Maywood

60612

Rush University Cancer Center, Chicago

80045

University of Colorado - Anschutz Cancer Pavilion, Aurora

90025

The Angeles Clinic and Research Institute, Los Angeles

90033

USC - Norris Comprehensive Cancer Center, Los Angeles

90095

UCLA Health - Westwood Cancer Care, Los Angeles

92093

University of California San Diego, Moores Cancer Center, La Jolla

94305

Stanford Cancer Institute, Stanford

02114

Massachusetts General Hospital, Boston

02215

Beth Israel Deaconess Medical Center, Boston

07962

Atlantic Health System - Morristown Medical Center, Morristown

M5G 2M9

Princess Margaret Cancer Centre, Toronto

CB2 0QQ

Cambridge University Hospital NHS Foundation Trust - Addenbrooke's Hospital, Cambridge

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Instil Bio

INDUSTRY

NCT05050006 - ITIL-168 in Advanced Melanoma | Biotech Hunter | Biotech Hunter