Screening for Individual Susceptibility Factors to Immersion Pulmonary Edema

NARecruitingINTERVENTIONAL
Enrollment

63

Participants

Timeline

Start Date

August 17, 2022

Primary Completion Date

August 31, 2026

Study Completion Date

August 31, 2026

Conditions
Pulmonary Edema
Interventions
OTHER

Terrestrial exercise

"At visit 1 (Day 0), an exercise test will be performed (maximal incremental test), followed by a 30-minute submaximal exercise at constant load.~During this exercise, continuous data collection will be performed:~* Continuous 12-lead electrocardiogram~* Continuous monitoring of blood pressure and ventilation."

OTHER

Swimming exercise

"At visit 2 (Day 7), the subjects will perform a swimming exercise in the experimental pool equipped with a turbine to create a counter-current. The water speed will be constant (4 min per 100 m, i.e. 1.5 km/h). The duration of the exercise will be 30 minutes. Each diver will breathe with the help of a snorkel.~During this exercise, continuous data collection will be performed:~* Continuous 12-lead electrocardiogram~* Continuous monitoring of blood pressure and ventilation."

DEVICE

Transthoracic cardiac ultrasound

The participants will have a transthoracic cardiac ultrasound to measure the dilatations of the cardiac cavities at visit 1 and 2.

DEVICE

Transthoracic pulmonary ultrasound

The participants will have a transthoracic pulmonary ultrasound to quantify the presence of signs of pulmonary vascular overload (comet tails) at visit 1 and 2.

BIOLOGICAL

Blood collection

Several blood samples will be collected at visit 1 and 2.

Trial Locations (2)

83800

RECRUITING

Equipe Résidente de Recherche Subaquatique Opérationnelle, Toulon

RECRUITING

Hôpital d'Instruction des Armées Sainte-Anne, Toulon

All Listed Sponsors
lead

Direction Centrale du Service de Santé des Armées

OTHER

NCT05049889 - Screening for Individual Susceptibility Factors to Immersion Pulmonary Edema | Biotech Hunter | Biotech Hunter