A Clinical Study of TK216 in Patients With Relapsed or Refractory Ewing's Sarcoma

PHASE2RecruitingINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

March 12, 2024

Primary Completion Date

September 13, 2025

Study Completion Date

December 31, 2025

Conditions
Sarcoma, Ewing
Interventions
BIOLOGICAL

TK216+Vincristin

TK216 was continuously administered for 14 days,then rest for 14 days. Vincristin is given before TK216 only in the first day of each cycle, the first cycle of VCR is 0.75mg/m\^2 and 1.5mg/m\^2 from the second cycle,every 28 days is a study cycle.

Trial Locations (8)

100005

RECRUITING

Union Hospital Tongji Medical College Huazhong University of Science and Technology, Wuhan

100044

RECRUITING

Peking University People's Hospital, Beijing

200233

RECRUITING

Shanghai Sixth People's Hospital, Shanghai

300060

RECRUITING

Tianjin Medical University Cancer Institude & Hospital, Tianjin

310003

RECRUITING

The Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou

410031

RECRUITING

Hunan Cancer Hospital, Changsha

450003

RECRUITING

Henan Cancer Hospital, Zhengzhou

RECRUITING

Henan Provincial People's Hospital, Zhengzhou

All Listed Sponsors
lead

Shanghai Pharmaceuticals Holding Co., Ltd

INDUSTRY