NCT05045261 - ANRS HB07 IP-Cure-B Proof of Concept (PoC) Clinical Trial. Educating the Liver Immune Environment Through TLR8 Stimulation Followed by NUC Discontinuation | Biotech Hunter

Enrollment

100

Participants

Timeline

Start Date

February 1, 2022

Primary Completion Date

June 30, 2024

Study Completion Date

June 30, 2024

Conditions

Hepatitis B, Chronic

Interventions

DRUG

administration of SLGN in arm C

administration of 3mg SLGN weekly for 24 weeks in arm C

DRUG

Discontinuation of NUC treatment in arms B and C

NUC treatment will be stopped after 28 weeks in arms B and C

Trial Locations (8)

13008

RECRUITING

Hepato-gastroenterology department, Hôpital Saint-Joseph, Marseille

20122

NOT_YET_RECRUITING

Gastroenterology and Hepatology Division, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan

43126

NOT_YET_RECRUITING

Department of General and Specialized Medical AreaAzienda Ospedaliera, University Hospital of Parma, Parma

54500

RECRUITING

Service d'Hépato-gastroentérologie, Hôpital de Brabois, Nancy

69004

RECRUITING

Hepatology Department, Hospices Civils de Lyon, Lyon

75013

RECRUITING

Service d'Hépato-gastroentérologie Hôpital Pitié Salpêtrière, Paris

79106

NOT_YET_RECRUITING

Department of Internal Medicine Clinic for Internal Medicine II - Gastroenterology, Hepatology, Endocrinology and Infectiology, Universitat Klinikum in Freiburg, Freiburg im Breisgau

08035

NOT_YET_RECRUITING

Internal Medicine and Hepatology, Vall d'Hebron University Hospital, Barcelona