Phase 2a MIB-626 vs. Placebo COVID-19

PHASE2CompletedINTERVENTIONAL
Enrollment

42

Participants

Timeline

Start Date

October 26, 2021

Primary Completion Date

August 17, 2023

Study Completion Date

August 17, 2023

Conditions
Covid19Stage 1 Acute Kidney Injury
Interventions
DRUG

MIB-626

Fifty participants will be randomized, stratified by sex, remdesivir use, and trial site, in a 3:2 ratio to receive either MIB-626 1.0 g orally or matching placebo twice daily for 14 days.

DRUG

Placebo

Subjects will be randomized to receive either the placebo or 1000-mg MIB-626 twice daily orally.

OTHER

Home Treatment

Participants, who are discharged from the hospital before the completion of the 14-day intervention period, will be provided sufficient study medication to take home with them so they can continue to take the medication twice daily for the remaining duration of the 14-day intervention period.

Trial Locations (1)

02115

The Brigham and Women's Hospital, Boston

All Listed Sponsors
lead

Metro International Biotech, LLC

INDUSTRY