120
Participants
Start Date
October 1, 2021
Primary Completion Date
January 1, 2026
Study Completion Date
September 1, 2026
NB004 tablets
"Part1: Dose escalation phase of study drug NB004 monotherapy:~Drug: NB004 tablets~NB004 tablets will be administered orally once daily for repeated 28-day cycles until discontinuation criteria are met.~Part 2: Dose Escalation Phase/ COMBO Dose Expansion Phase for the NB004 in combination with Sotorasib:~Drug: NB004 tablets \& Sotorasib~NB004 tablets will be administered orally once a daily for repeated 21-day cycles until discontinuation criteria are met.~Sotorasib will be administered with the recommended dosage per prescribing information approved by the FDA~Part 3: Dose Escalation Phase/ COMBO Dose Expansion Phase for the NB004 in combination with Sotorasib:~Drug: NB004 tablets \& Sotorasib~NB004 tablets will be administered orally once daily for repeated 21-day cycles until discontinuation criteria are met.~Sotorasib will be administered with the recommended dosage per prescribing information approved by the FDA ."
NOT_YET_RECRUITING
National Taiwan University Hospital Yunlin Branch, Yunlin
NOT_YET_RECRUITING
LSU-LCMC Health Cancer Center, New Orleans
RECRUITING
The University of Texas MD Anderson Cancer Center, Houston
RECRUITING
National Cheng Kung University Hospital(NCKUH), Tainan
Ningbo Newbay Technology Development Co., Ltd
INDUSTRY